| 名稱 | Recombinant Human BMP-4 |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | 骨形成蛋白(bmp)構成一個亞科內TGF-β總科的結構相關信號蛋白。這個總科的成員廣泛分布于整個身體,并參與各種生理過程在兩個前和產后的生活。像BMP-7 BMP-4參與骨骼和軟骨的開發和維護。BMP-4表達降低與許多骨相關疾病。} |
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一.產品名稱：Recombinant Human BMP-4
二.貨號Catalog Number:AF-120-05ET
三.同義Synonyms:BMP-2B, DVR4
四.描述Description:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body, and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. PeproTech’s E.coli-derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits, which correspond to amino acids 303-408 of the full length BMP-4 precursor. The calculated molecular weight of Recombinant Human BMP-4 (E.coli-derived) is 23.9 kDa. Manufactured using all non-animal reagents.
五.AA序列AA Sequence:
KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR
六.來源Source:E.coli
Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
七.生物活性Biological Activity:
Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.
八.交叉性Cross Reactivity:Mouse, Human, Rat
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室