| 名稱 | Recombinant Human FGF-acidic |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | FGF-acidic是23已知FGF家族的成員之一。這個家庭中發揮核心作用的蛋白質在產前發展和產后的生長和再生各種組織,通過促進細胞增殖和分化。FGF-acidic non-glycosylated肝素結合生長因子,表示在大腦中,腎、視網膜、平滑肌細胞,骨基質,成骨細胞、星形膠質細胞和內皮細胞。FGF-acidic有能力通過所有的FGF受體信號。} |
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- 詳細內容
一.產品名稱：Recombinant Human FGF-acidic
二.貨號Catalog Number:AF-100-17A
三.產地：美國Peprotech
四.同義Synonyms:Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
五.描述Description:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues. Manufactured using all non-animal reagents.
六.AA序列AA Sequence:
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
七.來源Source:E.coli
八.純度Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.
九.生物活性Biological Activity:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10ng/ml corresponding to a specific activity of ≥ 1 x 105 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
十.交叉性Cross Reactivity:
Cow, Mouse, Pig, Rat, Shark, Squid, Human
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室