| 名稱 | Recombinant Human IL-1β |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | IL-1β是各種細胞的促炎細胞因子產生包括單核細胞、組織巨噬細胞,角質細胞和其他上皮細胞。這些細胞因子刺激胸腺細胞增殖,誘導IL-2釋放,B-cell成熟和擴散,促有絲分裂的FGF-like活動和刺激前列腺素的釋放和膠原酶從滑膜細胞。然而,IL-1β而IL-1β是分泌細胞因子主要是cell-associated細胞因子。重組人類IL-1β17.3 kDa蛋白質含有153個氨基酸。} |
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- 詳細內容
一.產品名稱：Recombinant Human IL-1β/Peprotech IL-1β
二.Catalog Number:AF-200-01B
三.Synonyms:Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
四.Description:
IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1β is predominantly a cell-associated cytokine. Recombinant human IL-1β is a 17.3 kDa protein containing 153 amino acid residues. Manufactured using all non-animal reagents.
五.AA Sequence:
APVRSLNCTL RDSKSLVM SGPYELKALH LQGQDMEV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS
六.Source:E.coli
七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
八.Biological Activity:
Determined by its ability to stimulate the proliferation of mouse D10S cells. The expected ED50 is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 109 units/mg.
九.Cross Reactivity:
Frog, Monkey, Mouse, Rabbit, Rat, Sheep, Human
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室